Takahashi and Yamanaka, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Takahashi, Tanabe, et al., Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Van der Worp, Howells, et al., Can animal models of disease reliably inform human studies?
Warren, Tompkins, et al., Mice are not men.
Seok, Warren, et al., Genomic responses in mouse models poorly mimic human inflammatory diseases.
De Souza, Mouse model challenged.
Choi, Kim, et al., A three-dimensional human neural cell culture model of Alzheimer’s disease.
Hallett, Cooper, et al., Long-term health of dopaminergic neuron transplants in Parkinson’s disease patients.
Blurton-Jones, Kitazawa, et al., Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.
Mukherjee, Laws of Medicine (TED), p. 18.
Lapillonne, Kobari, et al., Red blood cell generation from human induced pluripotent stem cells.
Tang, Hammack, et al., Zika virus infects human cortical neural progenitors and attenuates their growth.
Paul Knoepfler in M. Scudellari, How iPS cells changed the world.
Глава пятнадцатая. Молодая кровь
McCay, Pope, et al., Parabiosis between old and young rats.
Learoyd, The history of blood transfusion prior to the 20th century.
Bert, Expériences et considérations sur la greffe animale.
I. M. Conboy, M. J. Conboy, et al., Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
Von Radowitz, Vampire therapy.
Villeda, Plambeck, et al., Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.
Villeda, Luo, et al., The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Harrison, Strong, et al., Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
De Grey, Ending Aging, p. 163
Глава шестнадцатая. Семена деменции
Braak and Del Tredici, Alzheimer’s pathogenesis.
Meyer-Luehmann, Coomaraswamy, et al., Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
Lipinski and Hopkins, Navigating chemical space for biology and medicine.
Eisele, Obermüller, et al., Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis.
R. M. Ridley, Baker, et al., Very long term studies of the seeding of beta-amyloidosis in primates.
Jaunmuktane, Mead, et al., Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy.
Prusiner, Madness and Memory, p. 202.
Чтобы развеять страхи, Министерство здравоохранения Великобритании открыло горячую телефонную линию для тех, кто получал человеческий гормон роста на основе вытяжки из гипофиза трупов и теперь опасается болезни Крейтцфельдта – Якоба и болезни Альцгеймера.
A. Miller, J. Dowd, M. D. Heath, S. M. D. Morris, S. Mosley, P. Nash, R. Williams et al., After the storm? UK blood safety and the risk of variant Creutzfeldt-Jakob Disease, House of Commons Science and Technology Committee, www.publications.parliament.uk/pa/cm201415/cmselect/cmsctech/327/327.pdf.
Anon., Alzheimergate? When miscommunication met sensationalism.
Gye, Chief medical officer is accused of trying to discredit impact of controversial study on Alzheimer’s before findings were published.
A. Abbott, The red-hot debate about transmissible Alzheimer’s.
Глава семнадцатая. Когда смотришь, но не видишь
Crutch, Lehmann, et al., Posterior cortical atrophy.
Pratchett, Shaking Hands with Death, p. 31.
Sacks, The Mind’s Eye, p. 19.
Crutch, Schott, et al., Shining a light on posterior cortical atrophy.
Whitlock, Sutherland, et al., Navigating from hippocampus to parietal cortex.
Breveglieri, Hadjidimitrakis, et al., Eye position encoding in three-dimensional space.
Глава восемнадцатая. Между Сциллой и Харибдой
Ariga, Common mechanisms of onset of cancer and neurodegenerative diseases.
Staropoli, Tumorigenesis and neurodegeneration.
J. Altman, Two faces of evil: cancer and neurodegeneration, Alzforum, http://www.alzforum.org/news/conference-coverage/ two-faces-evil-cancer-and-neurodegeneration.
Cramer, Cirrito, et al., ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models.
Stamps, Bartoshuk, Heilman, A brief olfactory test for Alzheimer’s disease.
Wang, Alzheimer’s families clamor for drug.
Pierrot, Lhommel, et al., Targretin improves cognitive and biological markers in a patient with Alzheimer’s disease.
Shen, Studies cast doubt on cancer drug as Alzheimer’s treatment.
Глава девятнадцатая. На краю земли
Сальвор Нордаль, Исландский университет. Цит. в E. J. Kirby, Iceland’s DNA: The world’s most precious genes? BBC, 2014, http://www.bbc.co.uk/news/magazine-27903831.
Smiley, The Sagas of the Icelanders.
Jonsson, Atwal, et al., A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline.
Power, Steinberg, et al., Polygenic risk scores for schizophrenia and bipolar disorder predict creativity.
K. W. Burton, Anti-Alzheimer’s gene may have led to the rise of grandparents, Science, http://www.sciencemag.org/news/2015/11/anti-alzheimer-s-gene-may-have-led-rise-grandparents.
Vassar, BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease.
Cummings, Morstorf, Zhong, Alzheimer’s disease drug-development pipeline.
Derek Lowe in M. Burke, Why Alzheimer’s drugs keep failing, Scientific American, https://www.scientificamerican.com/article/why-alzheimer-s-drugs-keep-failing/.
Глава двадцатая. Индийский опыт
Chandra, Ganguli, Ratcliff, et al., Studies of the epidemiology of dementia.
Hendrie, Osuntokun, et al., Prevalence of Alzheimer’s disease and dementia in two communities.
Hendrie, Hall, et al., Alzheimer’s disease is rare in Cree.
