Книга Кислород. Молекула, изменившая мир, страница 119. Автор книги Ник Лэйн

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Вирус простого герпеса и болезнь Альцгеймера


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Воспаление и болезнь Альцгеймера


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Mattson, М. Р. and Camandola, S. NFKB in neuronal plasticity and neurodegenerative disorders. Journal of Clinical Investigation 107: 247 — 254; 2001.


Табачный дым


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Диабет, гликирование и гены age


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Воспаление и атеросклероз


Becker, А. Е., de Boer, О. J. and van Der Wal А. С. The role of inflammation and infection in coronary artery disease. Annual Review of Меdicine 52: 289 — 297; 2001.


Окислительный стресс и воспаление при раке


Kovacic, P. and Jacintho, J. D. Mechanisms of carcinogenesis: focus on oxidative stress and electron transfer. Current Medical Chemistry 8: 773 — 796; 2001.

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Глава 15. Устойчивость к малярии


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Болезнь Альцгеймера в Нигерии


Hendrie, Н. С., Ogunniyi, А., Hall, К. S., et al. Incidence of dementia and Alzheimer disease in two communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana. Jоиrпаl оf the Атеriсап Medical Association 285: 739 — 747; 2001.

Farrer, L. А. Intercontinental epidemiology of Alzheimer disease. А global approach tо bad gene hunting. Jоиrпаl of thе Атеriсап Medical Association 285: 796 — 798; 2001.


Гемоксигеназа и подавление иммунитета


Taramelli, D., Recalcati, S., Basilico, N., Olliaro, Р. and Cairo, G. Macrophage preconditioning with synthetic malaria pigment reduces cytokine production via heme iron-dереndent oxidative stress. Laboratory Investigation 80: 1781 — 1788; 2000.

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Motterlini, R., Foresti, R., Bassi, R. and Green, С. J. Curcumin, an antioxidant and аnti-inflammatorу agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radical Biology and Medicine 28: 1303 — 1312; 2000.


Гигиеническая гипотеза


Rook, G. А. and Stanford, J. L. Give us this day our daily germs. Immunology Today 19: 113 — 116; 1998.


«Хрупкое здоровье» долгожителей


Yashin, А. I., De Benedictis, G., Vaupel, J. W., et al. Genes and longevity: lessons from studies of centenarians. Journal of Gеrопtology 55 А: В319 — В328; 2000.


Варианты митохондриальных генов и старение


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Цитоплазматический перенос и клонирование


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Липидный состав митохондрий


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Митохондриальная медицина


Hagen, Т., Ingersoll, R. Т., Wehr, С. М., Lykkesfeldt, J., Vinarsky, V., Bartholomew, J. C., Song M. H. and Ames В. N. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Proceedings of the National Academy of Sciепces USA 95: 9562 — 9566; 1998.

Hagen, Т. М., Liv, J., Lykkesfeldt, J., Wehr, С. М., Ingersoll, R. T., Vinarsky, V., Bartholomew, J. С. and Ames, В. N. Feeding acetyl-L-саrnitinе and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proceedings of the National Academy of Sciences USA 99: 1870 — 1875; 2002.

Brierley, E. J., Johnson, M. А., James, О. F. and Turnbull, D. М. Effects of physical activity and age on mitochondrial function. Quarterly Journal of Меdiсine 89: 251 — 258; 1996.

Fosslien, Е. Mitochondrial medicine — molecular pathology of defective oxidative phosphorylation. Annals of Сlinical Laboratory Science 31: 25 — 67; 2001.

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